Fatty Liver Index (FLI) is the best score to predict MASLD with 50% lower cut-off value in women than in men.
Lucilla CrudeleCarlo De MatteisFabio NovielliErsilia Di BuduoStefano PetruzzelliAlessia De GiorgiGianfranco AntonicaElsa BerardiAntonio MoschettaPublished in: Biology of sex differences (2024)
In this study, we found that FLI is the best non-invasive predictor of both liver steatosis and MASLD. The finding that in women FLI cut-off value for MASLD detection is 50% lower than in men suggests the need of a sex-specific personalized program of screening and prevention of dysmetabolism-related liver diseases, despite outwardly healthy biomarkers profile.