Prevention of hepatic encephalopathy by administration of rifaximin and lactulose in patients with liver cirrhosis undergoing placement of a transjugular intrahepatic portosystemic shunt (TIPS): a multicentre randomised, double blind, placebo controlled trial (PEARL trial).

Koos de WitJ J SchaapmanF NevensJ VerbeekS CoenenF J C CuperusM KramerE T T L TjwaN MostafaviM G W DijkgraafO M van DeldenU H W BeuersM J CoenraadR B Takkenberg

Published in: BMJ open gastroenterology (2021)

ClinicalTrials.gov (NCT04073290) and EudraCT database (2018-004323-37).

Keyphrases

double blind
phase iii
placebo controlled
clinical trial
study protocol
phase ii
early onset
pulmonary artery
open label
ultrasound guided
irritable bowel syndrome
randomized controlled trial
pulmonary arterial hypertension