IL-1 family cytokines and soluble receptors in systemic lupus erythematosus.

Paola ItalianiMaria Laura MancaFrancesca AngelottiDaniela MelilloFederico PratesiIlaria PuxedduDiana BoraschiPaola Migliorini

Published in: Arthritis research & therapy (2018)

The data support the use of IL-18, sIL-1R2 and sIL-1R4 as biomarkers of disease activity and organ involvement, and suggest that failure in the inhibition of IL-1 activation may be a critical event in the active stages of SLE.

Keyphrases

disease activity
systemic lupus erythematosus
rheumatoid arthritis
rheumatoid arthritis patients
ankylosing spondylitis
juvenile idiopathic arthritis
electronic health record
data analysis
deep learning
artificial intelligence