Human mesenchymal stem cell-derived extracellular vesicles/estrogen combined therapy safely ameliorates experimentally induced intrauterine adhesions in a female rat model.

Nesrine EbrahimOla MostafaRania Ebrahim El DosokyInas A AhmedAhmed S SaadAbeer MostafaDina SabryKhalid Abdelaziz IbrahimAyman Samir Farid

Published in: Stem cell research & therapy (2018)

We conclude that the synergistic action of human UCMSCs-EVs combined with estrogen provides a highly effective alternative regenerative agent in IUA treatment.

Keyphrases

endothelial cells
mesenchymal stem cells
high glucose
stem cells
induced pluripotent stem cells
pluripotent stem cells
estrogen receptor
bone marrow
diabetic rats
oxidative stress