High levels of immunoglobulin expression predict shorter overall survival in patients with acute myeloid leukemia.
Lina WuMiaoran XiaXiaoping SunXin HanYouli ZuElias J JabbourM James YouPei LinShaoying LiJie XuHaibo HanCarlos E Bueso-RamosL Jeffrey MedeirosXiaoyan QiuCheng Cameron YinPublished in: European journal of haematology (2020)
High levels of immunoglobulin expression are associated with monocytic differentiation, multilineage dysplasia, TET2 and KRAS mutations, and poor overall survival. Assessment of immunoglobulin may serve as a useful marker for prognostic stratification and target therapy.