Add-on effect of PSORI-CM01 to topical calcipotriol for moderate psoriasis vulgaris: A multi-center, randomized, double-blind pilot study.

Shefton ParkerAnthony Lin ZhangClaire Shuiqing ZhangGreg GoodmanZehuai WenYuhong YanDanni YaoHuimei WuHao DengChuanjian LuCharlie Changli Xue

Published in: Clinical and translational medicine (2021)

The design and duration of the study appears feasible. A proper powered RCT with slight adjustments in the methods is needed to reveal the add-on effects of oral CHM PSORI-CM01. The experience and results from this pilot study will contribute to the refine of objectives and design of a future study, and assist the sample size calculation for the full-scale RCT.

Keyphrases

double blind
placebo controlled
clinical trial
randomized controlled trial
phase iii
gene expression
phase ii
genome wide
monte carlo