Maternal left ventricular hypertrophy and diastolic dysfunction and brain natriuretic peptide concentration in early- and late-onset pre-eclampsia.
Vera Therezinha Medeiros BorgesS G ZanatiM T S PeraçoliJ R PoiatiM Romão-VeigaJ C PeraçoliB ThilaganathanPublished in: Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology (2018)
Early-onset PE is associated with more severe cardiac impairment than is late-onset PE, as evidenced by an increased prevalence of concentric hypertrophy, diastolic dysfunction and higher levels of BNP. These findings suggest that early-onset PE causes greater myocardial damage, increasing the risk of both peripartum and postpartum cardiovascular morbidity. Although these cardiovascular effects are easily identified by echocardiographic parameters and measuring BNP, further studies are needed to assess their clinical utility. Copyright © 2017 ISUOG. Published by John Wiley & Sons Ltd.
Keyphrases
- early onset
- left ventricular
- late onset
- oxidative stress
- hypertrophic cardiomyopathy
- cardiac resynchronization therapy
- left atrial
- acute myocardial infarction
- mitral valve
- heart failure
- aortic stenosis
- risk factors
- white matter
- resting state
- cerebral ischemia
- randomized controlled trial
- physical activity
- ejection fraction
- functional connectivity
- preterm birth
- pulmonary hypertension
- pregnant women
- aortic valve