"GLI1 Subcellular Localization and Overexpression as Prognostic Factors for Disease-Free Survival in Colorectal Carcinoma".

Tahseen Bilal RatherIshrat ParveizGowhar RashidKulsum AkhtarSyed MudassarRauf A WaniSyed BesinaRather Izhar Ul Haq

Published in: Journal of gastrointestinal cancer (2024)

High expression of GLI-1 in CRC is associated with adverse pathology and poor prognosis for patients. The correlation between cytoplasmic localization of GLI-1 and reduced disease-free survival holds potential for guiding prognosis and treatment. Further research is needed to develop strategies targeting GLI-1 for improved outcomes.

Keyphrases

free survival
poor prognosis
prognostic factors
long non coding rna
end stage renal disease
newly diagnosed
chronic kidney disease
cell proliferation
transcription factor
peritoneal dialysis
type diabetes
emergency department
metabolic syndrome
risk assessment
combination therapy
patient reported