Clinical phenotypes and outcomes of precapillary pulmonary hypertension of sickle cell disease.

Laurent SavaleAnoosha HabibiFrançois LionnetBernard Maitre Vincent CottinXavier JaisAri ChaouatElise Artaud-MacariMatthieu CanuetGrégoire PrevotChristelle Chantalat-AugerI David Montani Olivier SitbonFréderic GalacterosGérald SimonneauFlorence ParentPablo Bartolucci Marc Humbert

Published in: The European respiratory journal (2019)

Patients with precapillary PH related to SCD have a poor prognosis. Thrombotic lesions appear as a major component of PH related to SCD, more frequently in SC patients.

Keyphrases

pulmonary hypertension
poor prognosis
sickle cell disease
long non coding rna
end stage renal disease
pulmonary artery
newly diagnosed
ejection fraction
pulmonary arterial hypertension
chronic kidney disease
prognostic factors
metabolic syndrome
drug induced
insulin resistance