Movember GAP1 PDX project: An international collection of serially transplantable prostate cancer patient-derived xenograft (PDX) models.
Nora M NavoneWytske M van WeerdenRobert L VessellaElizabeth D WilliamsYuzhuo WangJohn T IsaacsHolly M NguyenZoran CuligGabri van der PluijmCyril A RentschRute B MarquesCorrina M A de RidderLukas BubendorfGeorge N ThalmannWilliam Nathaniel BrennenFrederic Romain SanterPatrizia L MoserPeter ShepherdEleni EfstathiouHui XueDong LinJeroen BuijsTjalling BosseAnne CollinsNorman MaitlandMark BuzzaMichelle KouspouAriel AchtmanRenea A TaylorGail RisbridgerEva CoreyPublished in: The Prostate (2018)
Our results demonstrate the clinical relevance of this series of PDXs as a platform for both basic science studies and therapeutic discovery/drug development. The present report provides the prostate cancer community with a summary of the basic characteristics and a contact information for collaborations using these models.