Immunohistochemistry reveals an increased proportion of MYC-positive cells in subcutaneous panniculitis-like T-cell lymphoma compared with lupus panniculitis.

Sebastian Fernandez-PolDanielle De StefanoJinah Kim

Published in: Journal of cutaneous pathology (2017)

Our work demonstrates that MYC expression levels differ between these 2 histologic mimics and suggests that this important oncoprotein may play a role in the pathogenesis of SPTCL.

Keyphrases

induced apoptosis
poor prognosis
transcription factor

systemic lupus erythematosus
cell cycle arrest
disease activity

cell death
binding protein
signaling pathway

rheumatoid arthritis
pi k akt
cell proliferation