Current aspects in the management of esophageal trauma: a systematic review and proportional meta-analysis.
Papakonstantinou DimitriosEmmanouil I KapetanakisAdam MylonakisSpyridon DavakisEfstathios KotidisEvangelos TagkalosIoannis RouvelasDimitrios SchizasPublished in: Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus (2024)
Trauma-related esophageal injuries (TEIs) are a rare but highly lethal condition. The presentation of TEIs is very diverse depending on the location and mechanism of injury (blunt vs. penetrating), as well as the presence or absence of concurrent injuries. The aim of the present systematic review and meta-analysis is to delineate the clinical features impacting TEI management. A systematic review of the Medline, Embase, and web of science databases was undertaken for studies reporting on patients with TEIs. A random effects model was employed in the meta-analysis of aggregated data. Eleven studies, incorporating 4605 patients, were included, with a pooled mortality rate of 19% (95% confidence interval (CI) 13-25%). Penetrating injuries were 34% more likely to occur (RR 0.66, 95% CI 0.49-0.89, P = 0.01), predominantly in the neck compartment. Surgery was employed in 53% of cases (95% CI 32-73%), with 68% of patients having associated injuries (95% CI 43-94%). In terms of choice of surgical repair technique, primary suture repair was most frequently reported, irrespective of injury location. Postoperative drainage was employed in 27% of the cases and was more common following repair of thoracic esophageal injuries. The estimated dependence on mechanical ventilation was 5.91 days (95% CI 5.1-6.72 days), while the length of stay in the intensive care unit averaged 7.89 days (95% CI 7.14-8.65 days). TEIs are uncommon injuries in trauma patients, associated with considerable mortality and morbidity. Open suture repair of ensuing esophageal defects is by large the most employed approach, while stenting may be indicated in carefully selected cases.
Keyphrases
- trauma patients
- end stage renal disease
- systematic review
- mechanical ventilation
- newly diagnosed
- chronic kidney disease
- minimally invasive
- prognostic factors
- peritoneal dialysis
- public health
- cardiovascular events
- electronic health record
- intensive care unit
- type diabetes
- randomized controlled trial
- acute respiratory distress syndrome
- patients undergoing
- spinal cord injury
- cardiovascular disease
- big data
- risk factors
- machine learning
- rectal cancer
- acute coronary syndrome
- study protocol
- ultrasound guided
- antiplatelet therapy
- surgical site infection