Idiopathic granulomatous mastitis: Looking for the most effective therapy with the least side effects according to the severity of the disease in 374 patients in Iran.
Ahmad KavianiMahtab VasighRamesh OmranipourHabibollah MahmoudzadehAhmad ElahiLeila FarivarSanaz ZandPublished in: The breast journal (2019)
The goal of this study is to compare the response rate and the recurrence rate of available therapeutic modalities in the treatment of Idiopathic Granulomatous Mastitis (IGM). 374 patients with pathologically confirmed IGM, were included. They were subdivided into three levels of severity. Close observation had the best response rate with the lowest recurrence rate in mild to moderate cases. Severe cases were mostly treated by prednisolone or underwent surgery. The outcome of prednisolone use in severe cases was comparable to NSAIDs. Overall 9% were resistant to treatment and surgical intervention is still an option among them.
Keyphrases
- end stage renal disease
- newly diagnosed
- randomized controlled trial
- chronic kidney disease
- early onset
- minimally invasive
- ejection fraction
- rheumatoid arthritis
- free survival
- stem cells
- acute coronary syndrome
- prognostic factors
- coronary artery disease
- atrial fibrillation
- drug induced
- percutaneous coronary intervention