Cell type-specific potential pathogenic genes and functional pathways in Alzheimer's Disease.

Published in: BMC neurology (2021)

Together, these analyses provide detailed information of cell type-specific and overall transcriptional changes and pathways underlying the human AD-pathology. These findings may provide important insights for drug development to tackle this disease.

Keyphrases

endothelial cells
gene expression
genome wide
cognitive decline
transcription factor
oxidative stress
risk assessment
pluripotent stem cells
climate change