Catalase deficiency facilitates the shuttling of free fatty acid to brown adipose tissue through lipolysis mediated by ROS during sustained fasting.
Raghbendra Kumar DuttaJoon No LeeYunash MaharjanChanny ParkSeong-Kyu ChoeYe-Shih HoRaekil ParkPublished in: Cell & bioscience (2021)
Taken together, our findings uncover the novel role of catalase in lipid metabolism and thermogenesis in BAT, which may be useful in understanding metabolic dysfunction.