Coffee and type 2 diabetes risk: Is the association mediated by adiponectin, leptin, c-reactive protein or Interleukin-6? A systematic review and meta-analysis.

Hasnaa Osama Mona A Abdelrahman Yasmin M Madney Hadeer S Harb Haitham Saeed Mohamed E A Abdelrahim

Published in: International journal of clinical practice (2021)

The present meta-analysis showed strong epidemiological evidence that coffee consumption is inversely associated with the risk of T2D. Also, adiponectin, leptin concentrations appeared to be potential mediators of the coffee effect on diabetes, while IL-6 levels did not.

Keyphrases

type diabetes
systematic review
insulin resistance
glycemic control
metabolic syndrome
cardiovascular disease
meta analyses
adipose tissue
randomized controlled trial
skeletal muscle