A magnetic resonance imaging modality for non-invasively distinguishing progression of liver fibrosis by visualizing hepatic platelet-derived growth factor receptor-beta expression in mice.
Ling WuXiao-Quan HuangNa LiCao XieSheng-Xiang RaoShi-Yao ChenFeng LiPublished in: Journal of gastroenterology and hepatology (2021)
Hepatic PDGFR-β expression reflects the progression of hepatic fibrosis, and MRI using Gd-labeled pPB as a tracer exhibits potential for distinguishing liver fibrosis staging in mice.
Keyphrases
- liver fibrosis
- growth factor
- magnetic resonance imaging
- poor prognosis
- high fat diet induced
- contrast enhanced
- binding protein
- pet imaging
- lymph node
- computed tomography
- diffusion weighted imaging
- long non coding rna
- pet ct
- risk assessment
- metabolic syndrome
- insulin resistance
- skeletal muscle
- human health
- living cells
- fluorescent probe