Outcomes reported in randomised clinical trials of major depressive disorder treatments in adolescents: a systematic scoping review protocol.
Andrea MonsourEmma J MewPeter SzatmariSagar PatelLeena SaeedMartin OffringaNancy J ButcherPublished in: BMJ open (2019)
The results of this review will inform the development of a COS for adolescent MDD. The development and implementation of a COS for RCTs evaluating interventions in adolescents with MDD promise to help reduce variability in trial outcome selection, definition, measurement and reporting, ultimately facilitating evidence synthesis that will help to identify the best treatment practices for adolescents with MDD.
Keyphrases
- major depressive disorder
- young adults
- clinical trial
- bipolar disorder
- physical activity
- primary care
- healthcare
- study protocol
- phase ii
- randomized controlled trial
- open label
- phase iii
- childhood cancer
- mental health
- machine learning
- adipose tissue
- quality improvement
- skeletal muscle
- combination therapy
- insulin resistance