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Association of Circulating Markers of Microbial Translocation and Hepatic Inflammation with Liver Injury in Patients with Type 2 Diabetes.

Leila GobejishviliVatsalya VatsalyaDiana V AvilaYana B FeyginCraig J McClainSriprakash MokshagundamShirish Barve
Published in: Biomedicines (2024)
These findings suggest that the pathogenic changes in the gut-liver axis, marked by increased microbial translocation, may be a major component in the etiology of hepatocyte inflammation and injury in patients with T2DM. However, larger longitudinal studies, including histological evidence, are needed to confirm these observations.
Keyphrases
  • liver injury
  • drug induced
  • oxidative stress
  • microbial community
  • cross sectional
  • metabolic syndrome
  • skeletal muscle
  • glycemic control
  • insulin resistance