Association of Circulating Markers of Microbial Translocation and Hepatic Inflammation with Liver Injury in Patients with Type 2 Diabetes.
Leila GobejishviliVatsalya VatsalyaDiana V AvilaYana B FeyginCraig J McClainSriprakash MokshagundamShirish BarvePublished in: Biomedicines (2024)
These findings suggest that the pathogenic changes in the gut-liver axis, marked by increased microbial translocation, may be a major component in the etiology of hepatocyte inflammation and injury in patients with T2DM. However, larger longitudinal studies, including histological evidence, are needed to confirm these observations.