High concentration of estradiol has a negative correlation with free thyroxine during the second trimester of pregnancy.

Leqi HeXiaoying LiZaoping ChenWei WangKai WangXinmei HuangQian YangWencai KeJun Liu Bingbing Zha

Published in: Endocrine connections (2022)

High concentration of E2 has a negative correlation with FT4. High concentration of E2 can inhibit the NIS expression through the ER-β-mediated pathway, which may cause thyroid hormone fluctuations during pregnancy.

Keyphrases

preterm birth
poor prognosis
estrogen receptor
pregnancy outcomes
binding protein