Octanol alleviates chronic constriction injury of sciatic nerve-induced peripheral neuropathy by regulating AKT/mTOR signaling.

Biquan DengHui ZouKeli HuYunlu LiuAchao Han

Published in: Journal of orthopaedic surgery (Hong Kong) (2024)

In conclusion, octanol can alleviate CCI-induced peripheral neuropathic by regulating the Akt/mTOR pathway and might be a novel pharmacological intervention for neuropathic pain.

Keyphrases

neuropathic pain
spinal cord
cell proliferation
spinal cord injury
high glucose
diabetic rats
signaling pathway
drug induced
randomized controlled trial
oxidative stress
endothelial cells
mouse model
stress induced
chemotherapy induced