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O-GlcNAcylation inhibits hepatic stellate cell activation.

Rui LiQunxiang OngChi Chun WongEagle S H ChuJoseph Jao Yiu SungXiaoyong YangJun Yu
Published in: Journal of gastroenterology and hepatology (2021)
Our results suggest that OGT functions as a negative regulator of HSC activation by promoting SRF O-GlcNAcylation to protect against liver fibrosis.
Keyphrases
  • liver fibrosis
  • single cell
  • cell therapy
  • transcription factor
  • stem cells
  • mesenchymal stem cells
  • bone marrow