The optimal immune checkpoint inhibitors combined with chemotherapy for advanced non-small-cell lung cancer: a systematic review and meta-analysis.
Y YangH LuoX L ZhengHong GePublished in: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico (2020)
ICIs + CT seemed to be more effective first-line regimen and PD-1 + CT could be recommended as the first-rank therapy for advanced NSCLC patients with low/negative expression of PD-L1. However, we should be particularly vigilant about the occurrence of the Grade 3-5 TRAEs.
Keyphrases
- advanced non small cell lung cancer
- epidermal growth factor receptor
- image quality
- dual energy
- computed tomography
- contrast enhanced
- poor prognosis
- positron emission tomography
- small cell lung cancer
- risk assessment
- magnetic resonance imaging
- locally advanced
- magnetic resonance
- tyrosine kinase
- squamous cell carcinoma
- brain metastases