Plasma levels of soluble HLA-G and cytokines in papillary thyroid carcinoma before and after thyroidectomy.
Bruna C BertolJéssica N G de AraújoIbrahim Abiodoun SadissouPaulin SononFabrício C DiasRaul Hernandes BortolinNathalie L de Figueiredo-FeitosaLuiz Carlos C de FreitasSheila R de Miranda Henrique TarrappCarlos C de Oliveira RamosAndre Ducati LuchessiJanaina C O C de FreitasLéa M Z MacielVivian Nogueira SilbigerEduardo Antônio DonadiPublished in: International journal of clinical practice (2020)
There are significant changes in the cytokine profile after surgical removal of the thyroid tumour, and IFN-α e TGF-β1 showed to be promising cytokines for discriminating PTC patients from controls. We also found that different cytokines are associated with clinicohistopathological characteristics of PTC related to poor prognosis, suggesting that cytokines seem to play an important role in PTC development and management.