Mesenchymal stem cells derived from human induced pluripotent stem cells improve the engraftment of myogenic cells by secreting urokinase-type plasminogen activator receptor (uPAR).
Ahmed ElhussienyKen'ichiro NogamiFusako Sakai-TakemuraYusuke MaruyamaNatsumi TakemuraWael Talaat SolimanShin'ichi TakedaYuko Miyagoe-SuzukiPublished in: Stem cell research & therapy (2021)
Our results indicate that iMSCs are a new tool to improve the engraftment of myogenic progenitors in dystrophic muscle.