Two Coxsackievirus B3 outbreaks associated with hand, foot, and mouth disease in China and the evolutionary history worldwide.

Zhenzhi HanYanjun ZhangKeqiang HuangJianxing WangHuifang TianYang SongQian YangDongmei YanShuangli ZhuMingxiao YaoXianjun WangWenbo Xu

Published in: BMC infectious diseases (2019)

Overall, our study indicated that CV-B3 is a causative agent of HFMD outbreak and revealed the phylogenetic dynamics of CV-B3 worldwide, as well as provided an insight on CV-B3 outbreaks for effective intervention and countermeasures.

Keyphrases

randomized controlled trial
infectious diseases
genome wide
single cell
dna methylation