High-Sensitivity and High-Throughput Quantification of Everolimus in Human Whole Blood Using Ultrahigh-Performance Liquid Chromatography Coupled With Tandem Mass Spectrometry.
Chika MiyagiRyota TanakaKenshiro HirataTakuma WatanabeRyosuke TatsutaShigeyuki MiyamuraHiroki ItohPublished in: Therapeutic drug monitoring (2022)
Therefore, the authors succeeded in developing a novel high-sensitivity and high-throughput method for measuring blood EVR concentration by UHPLC-MS/MS using a µElution plate for sample pretreatment.
Keyphrases
- tandem mass spectrometry
- high throughput
- ultra high performance liquid chromatography
- liquid chromatography
- ms ms
- high performance liquid chromatography
- simultaneous determination
- high resolution mass spectrometry
- mass spectrometry
- gas chromatography
- solid phase extraction
- liquid chromatography tandem mass spectrometry
- endothelial cells
- single cell
- high resolution
- induced pluripotent stem cells
- pluripotent stem cells