The Arabidopsis APOLO and human UPAT sequence-unrelated long noncoding RNAs can modulate DNA and histone methylation machineries in plants.
Camille Fonouni-FardeAurélie ChristThomas BleinMaría Florencia LegascueLucía FerreroMichaël MoisonLeandro LuceroJuan Sebastián Ramírez-PradoDavid LatrasseDaniel GonzalezMoussa BenhamedLeandro QuadranaMartin CrespiFederico D ArielPublished in: Genome biology (2022)
Collectively, our results uncover a new mechanism in which a plant lncRNA coordinates Polycomb action and DNA methylation through the interaction with VIM1, and indicates that evolutionary unrelated lncRNAs with potentially conserved structures may exert similar functions by interacting with homolog partners.
Keyphrases
- dna methylation
- genome wide
- transcription factor
- endothelial cells
- gene expression
- cord blood
- circulating tumor
- cell wall
- cell free
- long non coding rna
- copy number
- induced pluripotent stem cells
- single molecule
- high resolution
- pluripotent stem cells
- hiv testing
- nucleic acid
- network analysis
- genome wide identification
- men who have sex with men
- protein kinase
- hepatitis c virus
- mass spectrometry
- antiretroviral therapy
- human immunodeficiency virus