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Making HIS mice more human-like.

John A SimpsonMatthew E Brown
Published in: Journal of leukocyte biology (2019)
Discussion on exhaustion/senescence marker profiles on human T cells in BRGSF-A2 humanized mice and how they resemble those in human samples; describes how this model fits into the humanized-mouse research field.
Keyphrases
  • endothelial cells
  • induced pluripotent stem cells
  • pluripotent stem cells
  • metabolic syndrome
  • oxidative stress
  • monoclonal antibody
  • wild type