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Monitoring a Mandatory Nonmedical Switching Policy from Originator to Biosimilar Infliximab in Patients with Inflammatory Bowel Diseases: A Population-Based Cohort Study.

Anat FisherJason D KimColin R Dormuth
Published in: Gastroenterology research and practice (2023)
British Columbia's Biosimilars Initiative for nonmedical switching from originator to biosimilar infliximab for inflammatory bowel diseases was not associated with harmful impacts on medications and health services use. An increase in dose escalation was accompanied by an improvement in health status proxies.
Keyphrases
  • ulcerative colitis
  • public health
  • healthcare
  • quality improvement
  • mental health
  • open label
  • randomized controlled trial