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Salience and central executive networks track overgeneralization of conditioned-fear in post-traumatic stress disorder.

Hannah BergAngus W MacDonaldAmanda R RueterAntonia N KaczkurkinPhilip C BurtonColin G DeYoungAngus W MacDonald IiiScott R SponheimShmuel M Lissek
Published in: Psychological medicine (2020)
Neural substrates of generalized conditioned-fear include large-scale networks that adhere to the functional organization of the brain. Current findings implicate levels of generalization in SN and CEN as promising neural markers of PTSD.
Keyphrases
  • functional connectivity
  • resting state
  • social support
  • prefrontal cortex
  • white matter
  • working memory
  • posttraumatic stress disorder
  • depressive symptoms
  • multiple sclerosis
  • cerebral ischemia
  • blood brain barrier