miR-181a Upregulation Promotes Radioresistance of Nasopharyngeal Carcinoma by Targeting RKIP.

Wei HuangJie LiuShanbiao HuGuangqing ShiZhong YongJian LiJuan QiuYan CaoLi Yuan

Published in: OncoTargets and therapy (2019)

Collectively, the findings of this study proved that miR-181a is upregulated and promotes radioresistance by targeting RKIP in NPC. Targeting miR-181a/RKIP axis may be a valid path for reinforcing radiosensitivity and eventually improving the outcomes of clinical treatment in NPC.

Keyphrases

cell proliferation
long non coding rna
long noncoding rna
poor prognosis
dna damage response
cancer therapy
skeletal muscle
drug delivery
replacement therapy
glycemic control
dna repair