Alginates for Protection Against Pepsin-Acid Induced Aerodigestive Epithelial Barrier Disruption.

Tina L SamuelsKe YanNishma PatelKate PlehhovaCathal CoyleBryan P HurleyNikki Johnston

Published in: The Laryngoscope (2022)

GA and GDA preserved epithelial barrier function during pepsin-acid insult better than placebo suggesting that protection was due to alginate. These data support topical protection as a therapeutic approach to GERD and LPR. Laryngoscope, 132:2327-2334, 2022.

Keyphrases

pet ct
wound healing
electronic health record
big data
double blind
randomized controlled trial
clinical trial
phase iii
gastroesophageal reflux disease
placebo controlled
study protocol