Upc2-mediated mechanisms of azole resistance in Candida auris .

Jizhou LiLola AubryDanielle BrandaliseAlix T Coste Dominique Sanglard Frederic Lamoth

Published in: Microbiology spectrum (2024)

and shows that this effect is mediated via different pathways, including the regulation of ergosterol biosynthesis and also the direct upregulation of the drug transporter Mdr1.

Keyphrases

candida albicans
multidrug resistant
cell proliferation
poor prognosis
signaling pathway
emergency department
biofilm formation
escherichia coli
cystic fibrosis
pseudomonas aeruginosa
drug induced