Effects of a multidomain intervention against cognitive decline on dementia risk profiles - Results from the AgeWell.de trial.
Andrea E ZuelkeAlexander PabstMelanie LuppaAnke OeySolveig WeiseThomas FankhänelRobert P KosilekHannah SchillokChristian BrettschneiderDavid CzockBirgitt WieseJochen René ThyrianWolfgang HoffmannThomas FreseJochen GensichenHans-Helmut KönigHanna KaduszkiewiczSteffi G Riedel-HellerPublished in: Alzheimer's & dementia : the journal of the Alzheimer's Association (2024)
The AgeWell.de intervention reduced dementia risk according to LIfestyle for BRAin health (LIBRA) scores. Beneficial effects on LIBRA are mainly due to changes in diet and blood pressure. A pragmatic lifestyle intervention is apt to reduce dementia risk in an at-risk population.
Keyphrases
- mild cognitive impairment
- cognitive decline
- randomized controlled trial
- blood pressure
- physical activity
- weight loss
- cognitive impairment
- study protocol
- healthcare
- cardiovascular disease
- metabolic syndrome
- public health
- type diabetes
- multiple sclerosis
- adipose tissue
- brain injury
- heart rate
- resting state
- open label
- subarachnoid hemorrhage
- breast cancer risk