Low-Dose Spironolactone-Pioglitazone-Metformin Normalizes Circulating Fetuin-A Concentrations in Adolescent Girls with Polycystic Ovary Syndrome.

Marta DíazJosé Miguel Gallego-EscuredoAbel López-BermejoFrancis de ZegherFrancesc VillarroyaLourdes Ibañez

Published in: International journal of endocrinology (2018)

A low-dose combination of insulin sensitizers and an antiandrogen-but not oral contraception-normalizes fetuin-A levels in adolescent girls with PCOS. This trial is registered with ISRCTN29234515.

Keyphrases

low dose
high dose
type diabetes
study protocol
clinical trial
polycystic ovary syndrome
phase iii
phase ii
randomized controlled trial
glycemic control
insulin resistance