Anticancer drug 2-methoxyestradiol protects against renal ischemia/reperfusion injury by reducing inflammatory cytokines expression.
Ying-Yin ChenChing-Hua YehEdmund Cheung SoDing-Ping SunLi-Yun WangChung-Hsi HsingPublished in: BioMed research international (2014)
2ME2 reduces renal I/R injury in mice because it inhibits the expression of ROS and proinflammatory cytokines and induces antiapoptotic proteins.