ARL2 overexpression inhibits glioma proliferation and tumorigenicity via down-regulating AXL.

Yulin WangGefei GuanWen ChengYang JiangFengping ShanAnhua WuPeng ChengZongze Guo

Published in: BMC cancer (2018)

Our study suggests that ARL2 inhibits the proliferation, migration and tumorigenicity of glioma cells by regulating the expression of AXL and may conduct as a new prognostic and therapeutic target for glioma.

Keyphrases

tyrosine kinase
signaling pathway
poor prognosis
cell proliferation