Development and validation pathways of artificial intelligence tools evaluated in randomised clinical trials.

George C M SiontisRomy SwedaPeter A NoseworthyPaul A FriedmanKonstantinos C SiontisChirag J Patel

Published in: BMJ health & care informatics (2022)

We found significant variation in the patterns of development and validation for AI tools before their evaluation in dedicated AI-RCTs. Published peer-reviewed protocols and completed AI-RCTs were also heterogeneous in design and reporting. Upcoming guidelines providing guidance for the development and clinical translation process aim to improve these aspects.

Keyphrases

artificial intelligence
clinical trial
machine learning
big data
deep learning
open label
double blind
study protocol
randomized controlled trial