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Cytokeratin 7 Expression and Mismatch Repair Status for Survival Prediction in Patients With Low Rectal Cancer After Neoadjuvant Therapy.

Songli ShiMingming ZhouGang WangJinling XuDan ZhangMinying ZhengShiwu Zhang
Published in: Cancer control : journal of the Moffitt Cancer Center (2023)
The result confirms negative prognostic role of CK7-positive and dMMR statuses, which have potential predictive value for neoadjuvant chemoradiotherapy response. This provides opportunity to modify individualized treatment strategies for patients with different CK7 expression levels and dMMR statuses.
Keyphrases
  • rectal cancer
  • locally advanced
  • poor prognosis
  • protein kinase
  • squamous cell carcinoma
  • binding protein
  • lymph node
  • radiation therapy
  • long non coding rna
  • stem cells
  • mesenchymal stem cells
  • free survival
  • cell therapy