Triglyceride is independently correlated with insulin resistance and islet beta cell function: a study in population with different glucose and lipid metabolism states.
Minglei MaHaibin LiuJie YuShuli HePingping LiChunxiao MaHuabing ZhangLingling XuFan PingWei LiQi SunYu-Xiu LiPublished in: Lipids in health and disease (2020)
TG correlated with both insulin resistance and beta cell function in individuals with dyslipidemia alone. SOD negatively correlated with TG, indicating a close relationship between oxidative stress and glucose-lipid metabolism. Due to the adverse effect of hypertriglyceridemia on insulin sensitivity and islet beta cell function, more attention should be paid to the detection and management of hypertriglyceridemia.
Keyphrases
- insulin resistance
- oxidative stress
- adipose tissue
- high fat diet
- metabolic syndrome
- type diabetes
- blood glucose
- polycystic ovary syndrome
- skeletal muscle
- working memory
- fatty acid
- dna damage
- emergency department
- ischemia reperfusion injury
- amyotrophic lateral sclerosis
- signaling pathway
- weight loss
- quantum dots
- diabetic rats
- drug induced