Muscle-invasive bladder cancer in elderly and frail people: Is hypofractionated radiotherapy a feasible approach when no other local options are available?
Giulia MarvasoAngelo VitulloGiulia CorraoMaria Giulia VinciniMattia ZaffaroniRiccardo VillaFederico MastroleoLukasz KuncmanDario ZeriniIlaria RepettiChiara LorubbioGennaro MusiOttavio De CobelliBarbara Alicja Jereczek-FossaPublished in: Tumori (2024)
Our preliminary data demonstrate that palliative hypofractionated radiotherapy for bladder cancer in a frail and elderly population is technically feasible, with an acceptable toxicity profile. These outcomes emphasize the potential of this approach in a non-radical setting and could help to provide more solid indications in this underrepresented setting of patients.
Keyphrases
- radiation therapy
- community dwelling
- muscle invasive bladder cancer
- end stage renal disease
- early stage
- locally advanced
- middle aged
- newly diagnosed
- ejection fraction
- chronic kidney disease
- radiation induced
- peritoneal dialysis
- palliative care
- oxidative stress
- machine learning
- patient reported outcomes
- climate change
- brain metastases
- artificial intelligence
- insulin resistance
- human health
- advanced cancer
- patient reported