Upregulation of the ZNF148/PTX3 axis promotes malignant transformation of dendritic cells in glioma stem-like cells microenvironment.

Shan ChengLiang LiuDelin WangYongdong LiSuwen LiJiaqi YuanShilu HuangZhipeng XuBin JiaZhe LiJun Dong

Published in: CNS neuroscience & therapeutics (2023)

The ZNF148/PTX3 axis played an important role in regulating the malignant transformation of DCs after cross-talk with GSCs, and this axis may serve as a new target for sensitizing GBM to DC-based immunotherapy.

Keyphrases

dendritic cells
stem cells
immune response
poor prognosis
cell proliferation
regulatory t cells
long non coding rna