Cognitive decline in Parkinson's disease: the impact of the motor phenotype on cognition.

Jennifer WojtalaInes Ann HeberPetra NeuserJulia HellerElke KalbeSarah P RehbergAlexander StorchKatharina LinseChristine SchneiderSusanne GräberDaniela BergJudith DamsMonika Balzer-GeldsetzerRüdiger Hilker-RoggendorfCarola OberschmidtSimon BaudrexelKarsten WittNele SchmidtGünther DeuschlBrit MollenhauerClaudia TrenkwalderInga Liepelt-ScarfoneAnnika SpottkeSandra RoeskeUllrich WüllnerHans-Ulrich WittchenOliver RiedelRichard DodelJörg B SchulzKathrin Reetz

Published in: Journal of neurology, neurosurgery, and psychiatry (2018)

The three motor phenotypes of PD differ in cognitive performance, showing that cognitive deficits seem to be less severe in tremor-dominant PD. While these data are cross-sectional, longitudinal data are needed to shed more light on these differential findings.

Keyphrases

cognitive decline
mild cognitive impairment
cross sectional
electronic health record
big data
deep brain stimulation
early onset
multiple sclerosis
data analysis
white matter
deep learning