Cryptococcal antigenemia is associated with meningitis or death in HIV-infected adults with CD4 100-200 cells/mm3.

James H WykowskiSean R GalaganSabina GovereCarole L WallisMahomed-Yunus MoosaConnie CelumPaul K Drain

Published in: BMC infectious diseases (2020)

Although few PLWH with moderate immunosuppression screened CrAg positive, a positive CrAg test was predictive of increased risk of cryptococcal meningitis or death. Similar to those with a CD4 < 100 cell/mm3, systematic CrAg screening may reduce morbidity and mortality in PLWH with CD4 100-200 cells/mm3.

Keyphrases

induced apoptosis
hiv infected
cell cycle arrest
nk cells
cerebrospinal fluid
stem cells
antiretroviral therapy
cell therapy
cell death
single cell
human immunodeficiency virus
mesenchymal stem cells
bone marrow