Correlation of the surface expression of thymic stromal lymphopoietin receptor with the presence of CRLF2 gene rearrangements in children with B-lineage acute lymphoblastic leukemia.

Irina DeminaSvetlana LebedevaOlga SoldatkinaAnna KazakovaAlexandra SemchenkovaMaria GoncharovaGalina NovichkovaMichael MaschanAlexander KarachunskiyYulia OlshanskayaAlexander M Popov

Published in: International journal of laboratory hematology (2023)

When surface TSLPR is detected at the diagnosis of BCP-ALL, close attention should be given to the search for chromosomal aberrations involving CRLF2 at any level of expression.

Keyphrases

acute lymphoblastic leukemia
poor prognosis
copy number
binding protein
young adults
bone marrow
working memory
genome wide
long non coding rna
allogeneic hematopoietic stem cell transplantation
gene expression
transcription factor
genome wide analysis