Enhanced endoscopic detection of occult gastric cancer in carriers of pathogenic CDH1 variants.
Bryan Franklin CurtinLauren Ann GambleSamuel Ali SchuelerSamantha Marilyn RuffMartha QuezadoMarkku MiettinenGrace-Ann FasayeMonica PassiJonathan Matthew HernandezTheo HellerChristopher KohJeremy Lee DavisPublished in: Journal of gastroenterology (2020)
Gastric cancer detection was more frequent with implementation of a systematic surveillance protocol in CDH1 variant carriers. Given the decision for prophylactic surgery is often made by patients in the context of family history and pathologic result of surveillance biopsies, we propose the Bethesda protocol offers patients an opportunity to make more informed decisions.
Keyphrases
- end stage renal disease
- ejection fraction
- newly diagnosed
- randomized controlled trial
- public health
- prognostic factors
- primary care
- healthcare
- gene expression
- minimally invasive
- radiation therapy
- squamous cell carcinoma
- quality improvement
- patient reported
- label free
- acute coronary syndrome
- loop mediated isothermal amplification