Quantitative planar array screen of 1000 proteins uncovers novel urinary protein biomarkers of lupus nephritis.

Kamala VanarsaSanam SoomroTing ZhangBriony StrachanClaudia PedrozaMalavika NidhiPietro CicaleseChristopher GidleyShobha DasariShree MohanNathan ThaiVan Thi Thanh TruongNicole JordanRamesh SaxenaChaim PuttermanMichelle A Petri Chandra Mohan

Published in: Annals of the rheumatic diseases (2020)

Unbiased planar array screening of 1000 proteins has led to the discovery of urine Angptl4, L-selectin and TGFβ1 as potential biomarker candidates for tracking disease activity in LN.

Keyphrases

disease activity
high throughput
rheumatoid arthritis
systemic lupus erythematosus
high resolution
rheumatoid arthritis patients
ankylosing spondylitis
juvenile idiopathic arthritis
small molecule
transforming growth factor
single cell
high density
mass spectrometry
signaling pathway