Diversity and epitope spreading of anti-RNA polymerase III antibodies in systemic sclerosis: a potential biomarker for skin and lung involvement.
Hirohito KotaniKazuki Mitsuru MatsudaKei YamaguchiChihiro OnoEmi KogoKoji OgawaYuki KobayashiTeruyoshi HisamotoRuriko KawanabeAi KuzumiTakemichi FukasawaAsako Yoshizaki-OgawaNaoki GoshimaShinichi SatoAyumi YoshizakiPublished in: Arthritis & rheumatology (Hoboken, N.J.) (2024)
Our findings indicate a correlation between ES levels and the severity of skin sclerosis or the risk of other complications in SSc. This study suggests that measuring ES in SSc serves as a novel biomarker for disease activity.