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Substrate elasticity does not impact DNA methylation changes during differentiation of pluripotent stem cells.

Mohamed H Elsafi MabroukKira ZeevaertAnn-Christine HennekeCatharina MaaßenWolfgang Wagner
Published in: Cytotherapy (2024)
Stiffness of PDMS substrates did not affect directed differentiation of iPSCs, whereas the moderate epigenetic differences on TCP might also be attributed to other chemical parameters.
Keyphrases
  • dna methylation
  • pluripotent stem cells
  • gene expression
  • genome wide
  • high intensity
  • copy number
  • amino acid
  • induced pluripotent stem cells
  • structural basis